4-Nitro-2-(trifluoromethyl)aniline

Basic Information

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CAS Number

121-01-7

Molecular Formula

C7H5F3N2O2

Molecular Weight

206.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

90.0 to 94.0 deg-C

Boiling Point

298 °C at 760 mmHg

Flash Point

134 °C

Refractive Index

1.427

SMILES

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C1=CC(=C(C=C1[N+](=O)[O-])C(F)(F)F)N

InChI

InChI=1S/C7H5F3N2O2/c8-7(9,10)5-3-4(12(13)14)1-2-6(5)11/h1-3H,11H2

InChIKey

HOTZLWVITTVZGY-UHFFFAOYSA-N

LogP

3.30020

Complexity

226

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AC-6878
W-108465
SCHEMBL1532376
2-Trifluoromethyl-4-nitro-benzeneamine
4-nitro-2-trifluoromethylanilin
SB77437
DTXSID50153095
4-Nitro-alpha,alpha,alpha-trifluoro-o-toluidine
EN300-17348
AKOS000119238
A0805
MFCD00007365
Benzenamine, 4-nitro-2-(trifluoromethyl)-
2-Amino-5-nitro-trifluorobenzene
FT-0611184
2-trifluormethyl-4-nitroaniline
CS-W015340
Z56922111
EINECS 204-443-2
4-Nitro-2-(trifluoromethyl)aniline
4-Nitro-a,a,a-trifluoro-o-toluidine
AM20060300
BDBM626049
NS00041183
2-trifluoromethyl-4-nitroaniline
121-01-7
4-Nitro-2-trifluoromethyl-phenylamine
AS-12012
4-Nitro-2-(trifluoromethyl)aniline #
4-Nitro-2-trifluoromethylaniline
2-Amino-5-nitrobenzotrifluoride

MDL Number

MFCD00007365

Customs Code

2921430090

FAQ

What is 4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7)?

4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) is an aromatic amine with the chemical formula C7H6F3N2O2. It features a benzene ring substituted with a nitro group (-NO2) at the 4-position and a trifluoromethyl group (-CF3) at the 2-position. This compound is known for its stability, low solubility in water, and distinct chemical reactivity due to the electron-withdrawing nitro and trifluoromethyl groups.

What are the main uses of 4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7)?

4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) is primarily used as a chemical intermediate in pharmaceuticals, agrochemicals, and dyes. Its unique structure makes it valuable for synthesizing drugs targeting inflammatory diseases and as a precursor for fluorinated compounds. It is also employed in research for studying aromatic substitution reactions and material science applications.

Is 4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) safe?

4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) requires careful handling due to its potential toxicity. It may cause skin and respiratory irritation, so protective measures like gloves, goggles, and ventilation are essential. Safety standards emphasize avoiding inhalation of vapors and adhering to OSHA guidelines. Always refer to a safety data sheet (SDS) for proper disposal and emergency protocols.

How should 4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) be stored?

4-Nitro-2-(trifluoromethyl)aniline (CAS: 121-01-7) should be stored in a cool, dry, and well-ventilated area, away from light and moisture. Keep in a sealed, airtight container to maintain stability. Avoid contact with strong oxidizers or acids. Storage conditions should ensure long-term integrity, with temperature ideally below 25°C and humidity controlled to prevent degradation.