Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine | CAS No. 1206525-47-4

Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine

Basic Information

CAS Number

1206525-47-4

Molecular Formula

C62H91N17O21

Molecular Weight

1410.51 g/mol

EINECS

205-358-3

AD

Basic Physical Properties

Density

1.52±0.1 g/cm3(Predicted)

CC[C@H](C)[C@@H](C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)[C@H](Cc3ccc(cc3)O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CN

InChI

InChI=1S/C62H91N17O21/c1-6-30(4)50(78-56(94)40(21-32-13-15-34(82)16-14-32)74-55(93)42(23-48(86)87)71-47(85)27-69-52(90)37(70-46(84)25-63)12-9-19-67-62(65)66)59(97)76-41(22-33-26-68-36-11-8-7-10-35(33)36)54(92)77-44(28-80)58(96)73-39(20-29(2)3)53(91)75-43(24-49(88)89)57(95)79-51(31(5)81)60(98)72-38(61(99)100)17-18-45(64)83/h7-8,10-11,13-16,26,29-31,37-44,50-51,68,80-82H,6,9,12,17-25,27-28,63H2,1-5H3,(H2,64,83)(H,69,90)(H,70,84)(H,71,85)(H,72,98)(H,73,96)(H,74,93)(H,75,91)(H,76,97)(H,77,92)(H,78,94)(H,79,95)(H,86,87)(H,88,89)(H,99,100)(H4,65,66,67)/t30-,31+,37-,38-,39-,40-,41-,42-,43-,44-,50-,51-/m0/s1

InChIKey

HPPYJXKCLMBZCN-ZDQKBINTSA-N

LogP

-6.390330000000006

pKa

3.19±0.10(Predicted)

Topological Polar Surface Area

639.4899999999998 Ų

Hydrogen Bond Donor/Acceptor

26 / 38

Synonyms & References

English

  • Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine
  • Oligopeptide-68, beta-white
  • L-Glutamine, glycyl-L-arginylglycyl-L-α-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-α-aspartyl-L-threonyl-
  • Oligopeptide-68 CAS 1206525-47-4 Whitening Oligopeptide-68 Powder
  • Oligopeptide-68

EC Number

205-358-3

FAQ

What are the physical and chemical properties of Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine (CAS: 1206525-47-4)?

Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine is a peptide with a high molecular weight due to the presence of multiple amino acid residues. It is poorly soluble in water and has a crystalline form at room temperature. The compound exhibits limited reactivity under normal conditions but may require specific conditions for certain chemical reactions. Its physicochemical properties, including solubility and reactivity, make it suitable for use in pharmaceutical applications.

How is Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine (CAS: 1206525-47-4) typically synthesized?

Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine is typically synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves the stepwise addition of amino acids to an orthogonal protecting group. The final product is obtained after deprotection and cleavage from the resin, with yields and selectivity varying depending on the specific conditions and reagents used.

What industries use Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine (CAS: 1206525-47-4)?

Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine is primarily used in the pharmaceutical industry due to its potential in drug discovery and development. It can also be found in the biotechnology and research sectors, where it is used in various applications such as protein engineering and biomaterials. Its unique structure makes it valuable for specific applications in these industries.

What precautions should be taken when handling Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine (CAS: 1206525-47-4)?

When handling Glycyl-L-arginylglycyl-L-alpha-aspartyl-L-tyrosyl-L-isoleucyl-L-tryptophyl-L-seryl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-glutamine (CAS: 1206525-47-4), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats to prevent skin and eye contact. Work should be conducted in a fume hood to ensure proper ventilation. In case of a spill, it is recommended to immediately clean up the area using appropriate absorbents and dispose of waste according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling procedures and emergency response guidelines.

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