5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide | CAS No. 118904-15-7

5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide

Basic Information

CAS Number

118904-15-7

Molecular Formula

C30H44N10O6

Molecular Weight

640.75 g/mol

AD

Basic Physical Properties

CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)N)NC(=O)CNC(=O)C3CCC(=O)N3

InChI

InChI=1S/C30H44N10O6/c1-16(2)12-23(38-25(42)15-36-27(44)21-9-10-24(41)37-21)29(46)39-20(8-5-11-34-30(32)33)28(45)40-22(26(31)43)13-17-14-35-19-7-4-3-6-18(17)19/h3-4,6-7,14,16,20-23,35H,5,8-13,15H2,1-2H3,(H2,31,43)(H,36,44)(H,37,41)(H,38,42)(H,39,46)(H,40,45)(H4,32,33,34)/t20-,21-,22-,23-/m0/s1

InChIKey

MPGGTSBRFZJEKO-MLCQCVOFSA-N

LogP

-1.8553999999999942

Topological Polar Surface Area

268.78 Ų

Hydrogen Bond Donor/Acceptor

12 / 16

Complexity

1140

Synonyms & References

English

  • Antho-rwamide II
  • DTXSID70152262
  • L-Tryptophanamide, 5-oxo-L-prolylglycyl-L-leucyl-L-arginyl-
  • 5-Oxo-L-prolylglycyl-L-leucyl-L-arginyl-L-tryptophanamide
  • 118904-15-7
  • (2S)-N-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-5-oxopyrrolidine-2-carboxamide
  • Glu-gly-leu-arg-trp-NH2
  • L-Tryptophanamide,5-oxo-L-prolylglycyl-L-leucyl-L-arginyl- (9CI)
  • (2S)-N-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-5-oxopyrrolidine-2
  • Antho-RWamide II
  • PYR-GLY-LEU-ARG-TRP-NH2
  • 5-oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-L-tryptophanamide

MDL Number

MFCD02259604

FAQ

What regulatory guidelines apply to 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7)?

5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) is subject to the Globally Harmonized System (GHS) for classification and labeling of chemicals, REACH regulations in the European Union, and FDA/EPA requirements for pharmaceutical and environmental safety. Specific handling and disposal guidelines must be followed in accordance with local and international regulations.

Are there alternatives to 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) in synthesis?

In synthesis, alternatives to 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) include various amino acid derivatives and peptidomimetics. Common alternative reagents include similar peptides or their analogs, which can be used to achieve similar biological activities with varying degrees of efficacy and selectivity.

What is the market or research trend for 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7)?

The market for 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) is currently driven by its potential applications in pharmaceuticals and research. Emerging research trends focus on its use in targeted drug delivery, immunotherapy, and as a model compound for peptide chemistry. Market trends indicate increasing demand due to its unique chemical properties and potential therapeutic value.

How should waste containing 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) be handled?

Waste containing 5-Oxo-L-prolylglycyl-L-leucyl-N~5~-(diaminomethylene)-L-ornithyl-L-tryptophanamide (CAS: 118904-15-7) should be collected in appropriate containers and stored in a secure location. Proper incineration or professional waste disposal services should be utilized to ensure environmental safety. Handling should adhere to local and international environmental protection guidelines to minimize the risk of chemical exposure and contamination.

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