![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine | CAS No. 1188402-17-6
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine
Basic Information
CAS Number
1188402-17-6
Molecular Formula
C29H30N2O7
Molecular Weight
518.57 g/mol
AD
Basic Physical Properties
Boiling Point
751.6±60.0 °C(Predicted)
Density
1.279±0.06 g/cm3(Predicted)
Solubility
Insuluble (6.2E-3 g/L) (25 ºC),
Synonyms & References
English
- N-ALPHA-FMOC-L-ALANYL-N-ALPHA-(2, 4-DIMETHOXYBENZYL)-GLYCINE
- FMOC-ALA-(DMB)GLY-OH
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycine
- 2-[(2S)-N-[(2,4-dimethoxyphenyl)methyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]acetic acid
- Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]-
- N-(Fmoc-L-alanyl)-N-(2,4-dimethoxybenzyl)-glycine
- Nalpha-fmoc-L-alanyl-nalpha-(2, 4-dimethoxybenzyl)glycine
- Fmoc-ala-(dmb)gly-OH
MDL Number
MFCD08064314
Customs Code
2924297099
FAQ
What are the physical and chemical properties of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine (CAS: 1188402-17-6)?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine is a white crystalline compound with a molecular weight of approximately 645.47 g/mol. It has a solubility of about 1 g/L in water. Chemically, it is highly reactive, especially under acidic conditions, and is susceptible to hydrolysis. It is typically used as an intermediate in organic synthesis due to its functional groups.
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine (CAS: 1188402-17-6) typically synthesized?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine is synthesized through multi-step organic synthesis, involving acylation of a protected glycine derivative with fluorenylmethoxycarbonyl chloride, followed by coupling with an alanyl derivative. The reaction is typically carried out in the presence of a suitable base like triethylamine and a solvent such as dichloromethane. High purity can be achieved through column chromatography.
What industries use N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine (CAS: 1188402-17-6)?
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine is primarily used in the pharmaceutical industry as a precursor for the synthesis of more complex molecules. It is also utilized in the development of sensors and in the preparation of certain biodegradable polymers due to its unique chemical structure and reactivity.
What precautions should be taken when handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine (CAS: 1188402-17-6)?
Proper handling of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(2,4-dimethoxybenzyl)glycine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handling should be done in a fume hood to minimize exposure to vapors. Spills should be cleaned up carefully, using appropriate absorbent materials, and the area should be well ventilated. Safety data sheets (SDS) should be consulted for detailed safety guidelines.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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