(2S)-2-acetamidopentanedioic acid

Basic Information

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CAS Number

1188-37-0

Molecular Formula

C7H11NO5

Molecular Weight

189.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

194-196 °C

Boiling Point

495.9℃ at 760 mmHg

Water Solubility

2.7 g/100 mL (20 ºC)

Flash Point

253.7±25.9 °C

Solubility

36g/l (Lit.)

Refractive Index

-15 ° (C=1, H2O)

Specific Rotation

-16 º (c=1, water)

SMILES

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CC(=O)N[C@@H](CCC(=O)O)C(=O)O

InChI

InChI=1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1

InChIKey

RFMMMVDNIPUKGG-YFKPBYRVSA-N

LogP

-0.5594999999999994

Topological Polar Surface Area

103.7 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

225

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-Acetyl-L-glutamic acid
Acetyl-L-glutamic acid
AC-GLU-OH
Acetyl glutamic acid
l-glutamicaci
N-acetyl-Glu
n-acetylglutamate
n-acetylglutamic
n-acetylglutamicacid
N-ACETYL-L-GLU
N-Acetyl-L-glutamate
N-Acetyl-L-Glutamic
NAcGlu
N-AC-L-GLU
Glutamicacid, N-acetyl-, L- (6CI,7CI,8CI)
L-N-Acetylglutamicacid
N-Acetyl-L-glutaminic acid
N-Acetyl-S-glutamicacid
a-(N-Acetyl)-L-glutamicacid
N-乙酰-L-谷氨酸
Acetylglutamic acid
N-Acetylglutamic acid
L-Glutamic acid, N-acetyl-
L-N-Acetylglutamic acid
(2S)-2-acetamidopentanedioic acid
Glutamic acid, N-acetyl-, L-
Glutamic acid, N-acetyl- (6CI,7CI)
MA61H539YZ
Glutamic acid, N-acetyl-
(S)-2-acetamidopentanedioic acid
RFMMMVDNIPUKGG-YFKPBYRVSA-N

MDL Number

MFCD00002802

Customs Code

29241900

FAQ

What is (2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0)?

(2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) is a chiral organic compound with the chemical formula C6H11NO4. It features an acetamido group attached to the second carbon of a pentanedioic acid (glutaric acid) backbone. This compound is known for its stability and is commonly used as an intermediate in pharmaceutical and chemical synthesis. Its structure includes two carboxylic acid groups and an amino functional group, contributing to its reactivity and utility in various applications.

What are the main uses of (2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0)?

(2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) is primarily utilized in pharmaceuticals as a building block for drug synthesis, particularly in the development of antibiotics and antifungal agents. It also finds applications in industrial chemistry for producing polymers and coatings. In research settings, it serves as a key reagent for studying chiral compounds and functional group modifications. Its versatility makes it valuable in both organic synthesis and material science.

Is (2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) safe?

The safety of (2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) depends on handling conditions. It is generally considered low toxicity but may cause mild skin or eye irritation. Proper protective measures, such as gloves and safety goggles, are recommended during handling. Work in a well-ventilated area or fume hood to avoid inhalation. Always follow safety guidelines outlined in its Material Safety Data Sheet (MSDS) and adhere to OSHA and REACH regulations for safe use.

How should (2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) be stored?

(2S)-2-acetamidopentanedioic acid (CAS: 1188-37-0) should be stored in a cool, dry, and dark place, ideally at 25°C or below. Keep it in airtight containers to prevent moisture absorption and maintain stability. Avoid exposure to light and incompatible substances. Ensure storage areas are well-ventilated and follow standard chemical storage practices to preserve its integrity and ensure safety.