Login

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine | CAS No. 118362-03-1

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine

Basic Information

Chemical_Structure_Of
View in Editor

CAS Number

118362-03-1

Molecular Formula

C45H61N4O9PSi

Molecular Weight

17.03 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids
Basic Chemical Raw Materials Organic Chemicals Ethers
Basic Chemical Raw Materials Organic Chemicals Nitriles
Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates
Fine Chemicals Dyes and Pigments Organic Dyes
Fine Chemicals Surfactants Anionic Surfactants
Agricultural Chemicals Pesticides Insecticides
Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

InChI

InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1

InChIKey

SKNLXHRBXYGJOC-ZMHKPELYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Ų

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

1430

Synonyms & References

English

  • rUPhosphoramidite
  • DMT-2'O-TBDMS-rU Pharmadite(R)
  • AKOS015999123
  • 118362-03-1
  • DTXSID50447507
  • 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
  • 5/'-O-(4,4-Dimethoxytrityl)-2/'-O-[(tert-butyl)dimethylsilyl]uridine-3/'-(2-cyanoethyl-N,N-diisoprop
  • 144490-31-3
  • rU Phosphoramidite
  • C45H61N4O9PSi
  • AC-32374
  • DMT-2'O-TBDMS-rU Phosphoramidite, configured for MerMade
  • DMT-2'O-TBDMS-rU Phosphoramidite, configured for ABI
  • DMT-2'O-TBDMS-rU Phosphoramidite, configured for ??KTA(R) and OligoPilot(R)
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite
  • SCHEMBL667356
  • DMT-2'O-TBDMS-rU Phosphoramidite
  • (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-TBDMS-rU-3'-CEDPA
  • 2'-O-TERT-BUTYLDIMETHYLSILYL-5'-O-DMT-URIDINE 3'-CE PHOSPHORAMIDITE
  • 2'-TBDMS-rU-CE-Phosphoramidite
  • Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
  • (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5
  • 2'-O-(tert-butyldimethylsilyl)-5'-O-(p,p'-dimethoxytrityl)uridine 3'-[(2-cyanoethyl)N,N-diisopropylaminophosphoramidite]
  • 2'-O-tert-butyldimethylsilyl-5'-O-dimethoxytrityluridine 2-cyanoethyl-N,N-diisopropylphosphoramidite
  • 3'-O-[5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl-uridynyl]-2-cyanoethyl-(N,N-diisopropyl)phosphoramidite
  • 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • 2’-TBDMS-rU Phosphoramidite
  • DMT-2′O-TBDMS-rU Phosphoramidite
  • 5'-DMT-2'-TBDMS-rU Phosphoramidite

MDL Number

MFCD00080343

FAQ

What is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine (CAS: 118362-03-1)?
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine is a complex synthetic nucleoside derivative with a unique structure. It is used in various research applications and as an intermediate in the synthesis of other compounds. This compound is highly reactive and requires careful handling in a controlled environment.

What are the main uses of 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine (CAS: 118362-03-1)?
This compound is primarily used in pharmaceutical and chemical research as a precursor for the synthesis of other compounds. It is also utilized in the development of novel drugs and as a reagent in organic chemistry. Its specific applications include drug discovery and the synthesis of nucleoside analogs.

Is 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine (CAS: 118362-03-1) safe?
While 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine is safe for laboratory use when handled properly, it is important to follow all safety guidelines and precautions. This includes wearing appropriate personal protective equipment, working in a well-ventilated area, and disposing of waste properly.

How should 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine (CAS: 118362-03-1) be stored?
This compound should be stored in a cool, dry place away from direct light and heat. It should be kept in a tightly closed container, preferably under nitrogen to prevent oxidation and degradation. It is crucial to maintain a stable temperature and avoid exposure to moisture and air to ensure its integrity and safety during storage.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

Supplier Information

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine — Guangdong Wanzhang Chemical Reagent Co., Ltd.

Guangdong Wanzhang Chemical Reagent Co., Ltd.

CAS Number: 118362-03-1

View Details

MaAnShanZhiYanShengWuYiYao Technology Co Ltd

CAS Number: 118362-03-1

View Details

Nanjing Ancient Core Biotechnology Co., Ltd.

CAS Number: 118362-03-1

View Details

ShangHaiMaiKeLinShengHuaKeJi Inc

CAS Number: 118362-03-1

View Details

WuHanXinWeiYe Chemical Co Ltd

CAS Number: 118362-03-1

View Details
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine — Shanghai Titan Shareholding Technology Co., Ltd.

Shanghai Titan Shareholding Technology Co., Ltd.

CAS Number: 118362-03-1

View Details

Hangzhou Yaorieyicheng Biopharmaceutical Co., Ltd.

CAS Number: 118362-03-1

View Details

Shanghai Jieshukai Biotechnology Co., Ltd.

CAS Number: 118362-03-1

View Details

ShangHaiZhenZhun Biotechnology Co Ltd

CAS Number: 118362-03-1

View Details

Shanghai Tengzhun BioScience Co., Ltd.

CAS Number: 118362-03-1

View Details
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine — ShangHaiMaiRuiErShengHua Technology Co Ltd

ShangHaiMaiRuiErShengHua Technology Co Ltd

CAS Number: 118362-03-1

View Details

ZhengZhouAErFa Chemical Co Ltd

CAS Number: 118362-03-1

View Details
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine — HePeng （ ShangHai ） Biotechnology Co Ltd

HePeng （ ShangHai ） Biotechnology Co Ltd

CAS Number: 118362-03-1

View Details

ShangHaiXiangGengKeJi Development Co Ltd

CAS Number: 118362-03-1

View Details

Qingdao Juddian Technology Co., Ltd.

CAS Number: 118362-03-1

View Details

This website uses cookies to ensure basic functionality and enhance your experience. We use:

  • Essential cookies: Required for core site features (authentication, security). These cannot be disabled.
  • Analytics cookies: Help us understand site usage to improve our service.

You can change your preferences at any time in our Privacy Settings. See our Privacy Policy for more details.