![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione | CAS No. 1174157-65-3
1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione
Basic Information
CAS Number
1174157-65-3
Molecular Formula
C10H11NO5
Molecular Weight
225.2 g/mol
AD
Chemical Classification
Basic Physical Properties
Physical State
Solid powder
Melting Point
36-41 °C
Water Solubility
Slightly soluble in water.
Synonyms & References
English
- 2,5-dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate
- Propargyl-N-hydroxysuccinimidyl ester
- PROPARGYL-NHS 3-(PROP-2-YNYLOXY)PROPANOIC ACID SUCCINIMIDYL ESTER
- 3-(2-Propyn-1-yloxy)propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
- Alkyne-NHS ester
- Propargyl-succinimidyl-ester
- 2,5-Dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate
- Propargyl-PEG1-NHS ester
MDL Number
MFCD13184973
FAQ
What are the physical and chemical properties of 1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione (CAS: 1174157-65-3)?
1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione is a crystalline compound with a molecular weight of approximately 346.28 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. The compound is reactive towards nucleophiles and can undergo various chemical transformations. It is stable under normal storage conditions but may degrade under acidic or basic conditions.
How is 1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione (CAS: 1174157-65-3) typically synthesized?
1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione can be synthesized via a multi-step process, starting with the preparation of the 2-propyn-1-yl alcohol, followed by its esterification with 3-(2-propyn-1-yloxy)propanoic acid. The reaction is typically performed under mild conditions using appropriate catalysts to ensure high selectivity and yield. Detailed procedures are available in the literature and can be adapted for industrial-scale production.
What industries use 1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione (CAS: 1174157-65-3)?
1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry for the modification of polymer properties. Additionally, it is used in the development of sensors and semiconductors, where its reactivity and molecular structure make it suitable for specific functionalization processes.
What precautions should be taken when handling 1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione (CAS: 1174157-65-3)?
When handling 1-{[3-(2-Propyn-1-yloxy)propanoyl]oxy}-2,5-pyrrolidinedione, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up carefully according to the Material Safety Data Sheet (MSDS/SDS) guidelines. Ensure that the compound is stored in a cool, dry place away from incompatible materials and flammable substances. Always follow safety protocols and refer to the latest MSDS for detailed information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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