TFA-ap-dU | CAS No. 115899-40-6

TFA-ap-dU

Basic Information

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CAS Number

115899-40-6

Molecular Formula

C14H14F3N3O6

Molecular Weight

377.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1C(C(OC1N2C=C(C(=O)NC2=O)C#CCNC(=O)C(F)(F)F)CO)O

InChI

1S/C14H14F3N3O6/c15-14(16,17)12(24)18-3-1-2-7-5-20(13(25)19-11(7)23)10-4-8(22)9(6-21)26-10/h5,8-10,21-22H,3-4,6H2,(H,18,24)(H,19,23,25)/t8-,9+,10+/m0/s1

InChIKey

HCKMZBZCHQQZRJ-IVZWLZJFSA-N

Complexity

708

Synonyms & References

English

Uridine, 2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-
TFA-ap-dU
2'-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine
5-TFA-AP-DU
5-TFA-ap-2'-Deoxyuridine
2,2,2-Trifluoro-N-[3-[1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]
AK163056
HCKMZBZCHQQZRJ-IVZWLZJFSA-N
AX8294826
5-(3-trifluoroacetamidopropynyl)-2'-deoxyuridine
alpha-[2-(Trifluoroacetylamino)ethylidyne]thymidine
5-[3-(Trifluoroacetamido)-propynyl]-2'-deoxyuridine
2'-Deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-uridine
5-[3-(2,2,2-trifluoroacetamido)-prop-1-ynyl]-2'-deoxyuridine
2'-Deoxy-5-[3-[
2'-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino
2,2,2-trifluoro-N-[3-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2,4-dioxo-pyrimidin-5-yl]prop-2-ynyl]acetamide
A893769
2,2,2-trifluoro-N-[3-[1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynyl]acetamide
115899-40-6
SCHEMBL2030380
DS-8001
2,2,2-TRIFLUORO-N-(3-{1-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-2,4-DIOXO-3H-PYRIMIDIN-5-YL}PROP-2-YN-1-YL)ACETAMIDE
C71506
J-700301
2,2,2-trifluoro-N-(3-{1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl}prop-2-yn-1-yl)acetamide
CS-0149679
AKOS024464706
AC-32324

MDL Number

MFCD28134648

FAQ

What is TFA-ap-dU (CAS: 115899-40-6)?

TFA-ap-dU, also known as 2'-fluoro-1,3-dithiolan-2-one-4-acetate-5-ureido derivative, is a chemical compound used primarily in the field of nucleic acid chemistry and drug discovery. It is a key reagent in the synthesis of modified nucleotides and DNA analogs.

What are the main uses of TFA-ap-dU (CAS: 115899-40-6)?

TFA-ap-dU is mainly used in the pharmaceutical and research industries for the synthesis of modified nucleotides and DNA analogs. It plays a crucial role in the development of nucleic acid-based therapeutics and research tools.

Is TFA-ap-dU (CAS: 115899-40-6) safe?

TFA-ap-dU is generally considered safe when handled with appropriate precautions. However, exposure to the compound may cause skin irritation and respiratory issues. Protective measures such as gloves, goggles, and a fume hood should be used to minimize risk.

How should TFA-ap-dU (CAS: 115899-40-6) be stored?

TFA-ap-dU should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and contamination. Refrigeration is not necessary but can extend its shelf life.