N-[(Benzyloxy)carbonyl]serine

Basic Information

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CAS Number

1145-80-8

Molecular Formula

C11H13NO5

Molecular Weight

239.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

117.0 to 120.0 deg-C

Boiling Point

381.88°C (rough estimate)

Flash Point

248.6 °C

Refractive Index

6.1 ° (C=6, AcOH)

Specific Rotation

6 º (c=7, AcOH)

SMILES

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C1=CC=C(C=C1)COC(=O)NC(CO)C(=O)O

InChI

InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

InChIKey

GNIDSOFZAKMQAO-VIFPVBQESA-N

LogP

0.3582999999999999

Topological Polar Surface Area

95.86 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

263

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-W007842
CBZ-L-SERINE
MFCD00002662
1145-80-8
N-Benzyloxycarbonylserine
(2S)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxypropanoic acid
N-Carbobenzyloxy-L-serine
48KP4476DJ
(2S)-2-(((BENZYLOXY)CARBONYL)AMINO)-3-HYDROXYPROPANOIC ACID
Q-101649
N-Benzyloxycarbonyl-l-serin
EN300-97120
HY-W007842
Z-Ser-OH
N-((PHENYLMETHOXY)CARBONYL)SERINE
NS00023715
n-[(benzyloxy)carbonyl]-l-serine
L-SERINE, N-CARBOXY-, N-BENZYL ESTER
CHEMBL1222399
(2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid
L-Serine, N-[(phenylmethoxy)carbonyl]-
N-(Benzyloxycarbonyl)-L-serine
Z-L-Serine
NSC-286604
L-CARBOBENZYLOXY SERINE
(2S)-2-((BENZYLOXYCARBONYL)AMINO)-3-HYDROXYPROPANOIC ACID
Benzyloxycarbonylserine
L-Serine, N-benzyloxycarbonyl-
AM20060489
AS-12751
AC-7344

MDL Number

MFCD00002662

Customs Code

2924299090

FAQ

What is N-[(Benzyloxy)carbonyl]serine (CAS: 1145-80-8)?

N-[(Benzyloxy)carbonyl]serine, also known as benzyloxycarbonylserine, is a protected amino acid derivative with the chemical formula C14H19NO4. It is used as a protective group in peptide synthesis to prevent side reactions during the coupling steps.

What are the main uses of N-[(Benzyloxy)carbonyl]serine (CAS: 1145-80-8)?

N-[(Benzyloxy)carbonyl]serine is primarily used in the synthesis of peptides and proteins. It serves as a protecting group to avoid unwanted side reactions, such as esterification or amide formation, during the peptide assembly process. It is also used in research for the study of enzyme kinetics and catalysis.

Is N-[(Benzyloxy)carbonyl]serine (CAS: 1145-80-8) safe?

N-[(Benzyloxy)carbonyl]serine is generally considered safe for laboratory use when handled properly. However, it should be stored in a cool, dry place away from direct sunlight. Avoid contact with skin and eyes. Use appropriate personal protective equipment such as gloves and goggles during handling.

How should N-[(Benzyloxy)carbonyl]serine (CAS: 1145-80-8) be stored?

N-[(Benzyloxy)carbonyl]serine should be stored in a cool, dry place, ideally between 15-25°C. Keep it away from direct sunlight and moisture. Store it in a tightly sealed container to prevent degradation. It is crucial to handle it under proper ventilation conditions to avoid inhaling the vapors.