Fmoc-2-Nal-OH | CAS No. 112883-43-9

Fmoc-2-Nal-OH

Basic Information

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CAS Number

112883-43-9

Molecular Formula

C28H23NO4

Molecular Weight

437.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

155 ºC

Boiling Point

549.64°C (rough estimate)

Water Solubility

Slightly soluble in water.

Flash Point

371.6 °C

Refractive Index

1.6290 (estimate)

SMILES

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OC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)OCC3c4ccccc4-c5ccccc35

InChI

InChI=1S/C28H23NO4/c30-27(31)26(16-18-13-14-19-7-1-2-8-20(19)15-18)29-28(32)33-17-25-23-11-5-3-9-21(23)22-10-4-6-12-24(22)25/h1-15,25-26H,16-17H2,(H,29,32)(H,30,31)/t26-/m0/s1

InChIKey

JYUTZJVERLGMQZ-SANMLTNESA-N

LogP

5.3742000000000045

Topological Polar Surface Area

75.63000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

668

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Fmoc-3-(2-Naphthyl)-L-alanine
N-(9-Fluorenylmethoxycarbonyl)-2-naphthyl-L-alanine
Fmoc-3-(2-naphthyl)-alanine
N-Fmoc-3-(2-naphthyl)-L-alanine
Fmoc-2-Nal-OH
(S)-N-Fmoc-3-(2-naphthyl)alanine
Fmoc-beta-(2-naphthyl)-L-alanine
Fmoc-L-2Nal-OH
Fmoc-L-2-Naphthylalanine
FMOC-NAL(2)-OH
Fmoc-L-2-Nal
FMOC-L-NAL(2)
FMOC-ALA(2-NAPH)-OH
RARECHEM BK PT 0099
FMOC-ALA(2-NAPHTHYL)-OH
Fmoc-L-Ala(2-naphthyl)-OH
FMOC-L-3-(2-NAPTHYL)ALANINE
FMOC-2-NAL-OH
FMOC-L-2NAL-OH
FMOC-L-2-NAPHTHYLALANINE

MDL Number

MFCD00144886

Customs Code

2924299090

FAQ

What regulatory guidelines apply to Fmoc-2-Nal-OH (CAS: 112883-43-9)?

Fmoc-2-Nal-OH (CAS: 112883-43-9) falls under the regulatory oversight of the Chemicals in Products Regulation (CIPR) and the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) in the European Union. In the United States, it is subject to regulations by the Occupational Safety and Health Administration (OSHA), the Environmental Protection Agency (EPA), and the Food and Drug Administration (FDA). Compliance with GHS (Globally Harmonized System of Classification and Labelling of Chemicals) is also necessary for proper hazard communication and handling.

Are there alternatives to Fmoc-2-Nal-OH (CAS: 112883-43-9) in synthesis?

While Fmoc-2-Nal-OH (CAS: 112883-43-9) is a specific compound, alternatives include other amino acid derivatives such as Fmoc-Asp-OH and Fmoc-Val-OH, which are commonly used in solid-phase peptide synthesis. These alternatives may offer similar functional group reactivity but with different side chain properties. Additionally, other protected amino acids like Boc-2-Nal-OH are also available and can be considered as substitutes.

What is the market or research trend for Fmoc-2-Nal-OH (CAS: 112883-43-9)?

The market for Fmoc-2-Nal-OH (CAS: 112883-43-9) is driven by its use in solid-phase peptide synthesis for drug discovery and biotechnology applications. Recent research trends indicate an increasing focus on peptide-based therapeutics, which has stimulated demand for this compound. Additionally, there is a growing interest in developing new synthetic methods and reagents to improve the efficiency and scalability of peptide synthesis.

How should waste containing Fmoc-2-Nal-OH (CAS: 112883-43-9) be handled?

Waste containing Fmoc-2-Nal-OH (CAS: 112883-43-9) should be handled according to the principles of the Waste Management Hierarchy: reduce, reuse, recycle, and dispose. In practice, this involves minimizing waste generation, utilizing it for further synthesis if possible, and then disposing of it through professional waste disposal services. Proper collection, storage, and hazardous waste disposal procedures should be followed, adhering to local and national regulations. Environmental protection measures, such as neutralization of acidic or basic residues, are also crucial to prevent environmental contamination.