Sparfloxacin | CAS No. 111542-93-9

Sparfloxacin

Basic Information

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CAS Number

111542-93-9

Molecular Formula

C19H22F2N4O3

Molecular Weight

392.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1CN(CC(N1)C)C2=C(C(=C3C(=C2F)N(C=C(C3=O)C(=O)O)C4CC4)N)F

InChI

InChI=1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+

InChIKey

DZZWHBIBMUVIIW-DTORHVGOSA-N

LogP

2.5

Topological Polar Surface Area

100.58999999999999 Å²

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

691

Synonyms & References

English

NCGC00166294-02
cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Sparfloxacinum
Epitope ID:119065
5-amino-1-cyclopropyl-6,8-difluoro-7-(cis-3,5-dimethyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
MFCD00869619
SR-05000001521-1
5-Amino-1-cyclopropyl-7-(cis-3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
AT4140
AT-4140 pound>>CI-978 pound>>CI 978 pound>>CI978 pound>>AT 4140 pound>>AT4140 pound>>PD 131501 pound>>PD131501 pound>>PD-131501
GTPL10860
5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Sparfloxacine (INN-French)
C19H22F2N4O3
s1884
5-amino-1-cyclopropyl-7-[(3S,5R)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-4-oxo-3-quinolinecarboxylic acid
NCGC00166294-03
PD131501
SPARFLOXACIN [USAN]
SPARFLOXACIN [WHO-DD]
SPARFLOXACIN [VANDF]
AB00639950_03
Sparfloxacine [INN-French]
SR-01000759357
SPARFLOXACIN [INN]
SMR000466312
C07662
Sparfloxacinum [INN-Latin]
SR-01000759357-2
sparfloxacin
AT 4140

FAQ

What are the physical and chemical properties of Sparfloxacin (CAS: 111542-93-9)?

Sparfloxacin (CAS: 111542-93-9) is a crystalline compound with a molecular weight of approximately 417.4 g/mol. It is poorly soluble in water but soluble in organic solvents. Sparfloxacin exhibits limited reactivity under normal conditions, with a low tendency to undergo hydrolysis. It is stable under acidic and basic conditions but should be handled in a fume hood to avoid inhalation exposure.

How is Sparfloxacin (CAS: 111542-93-9) typically synthesized?

Sparfloxacin (CAS: 111542-93-9) is synthesized through a multi-step reaction involving condensation, ring-opening, and alkylation steps. The key catalysts include triphenylphosphine and sodium hydride. The overall yield is around 75%, and the method is highly selective, making it suitable for industrial production in the pharmaceutical industry.

What industries use Sparfloxacin (CAS: 111542-93-9)?

Sparfloxacin (CAS: 111542-93-9) is primarily used in the pharmaceutical industry as an antibiotic. It is also relevant in research and development for its antimicrobial properties. Due to its selective nature, it is sometimes used in the formulation of topical and oral medications.

What precautions should be taken when handling Sparfloxacin (CAS: 111542-93-9)?

When handling Sparfloxacin (CAS: 111542-93-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, immediately clean up using appropriate solvents and dispose of waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.