N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine | CAS No. 110764-78-8

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine

Basic Information

CAS Number

110764-78-8

Molecular Formula

C47H54N5O9P

Molecular Weight

863.9 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (3.8E-5 g/L) (25 ºC),

CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

InChI

InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-42-40(60-45(43(42)57-7)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1

InChIKey

JFFSFQRVIPPCBC-VKBHKTMGSA-N

Complexity

1500

Synonyms & References

English

  • N-blocked-5/'-O-DMT-2/'-O-Me CED cytosine phosphoramidite
  • N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl diisopropylphosphoramidite)
  • 110764-78-8
  • MFCD00792624
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methylcytidine
  • BP-40051
  • N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
  • HY-138578
  • (2R,3R,4R,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
  • SCHEMBL6928627
  • E85510
  • DTXSID00551648
  • CS-0159224
  • J-700068
  • 2'-O-Me-C(Bz) Phosphoramidite
  • PD157758
  • AKOS016003787
  • N-{1-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide
  • N4-Bz-5'-O-DMTr- 2'-O-Me-cytidine-3'-CED-phosphoramidite
  • 2'-OMe-Bz-C Phosphoramidite
  • AC-32380
  • Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
  • 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine-3'-CE-Phosphoramidite
  • Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-,3'-[2-cyanoethyl bis(1...
  • Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (
  • AK-54675
  • ANW-64066
  • CTK8C0083
  • SureCN6928627
  • N-[1-[5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphan

MDL Number

MFCD00792624

FAQ

What regulatory guidelines apply to N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8)?

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) is subject to regulations such as GHS for classification and labelling, REACH for registration, evaluation, authorization, and restriction of chemicals, and FDA/EPA requirements for pharmaceutical and chemical manufacturing. Compliance with these guidelines ensures safe handling and use.

Are there alternatives to N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) in synthesis?

Synthesis alternatives for N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) include using analogous cytidine derivatives or modifying the phosphorus-containing moiety. Common alternatives involve changing the substituents or using different protecting groups.

What is the market or research trend for N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8)?

The research trend for N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) focuses on its potential as a chemical probe or pharmaceutical intermediate. Market trends indicate increasing interest in its applications in drug discovery and development, particularly in targeted cancer therapies.

How should waste containing N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) be handled?

Waste containing N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-methylcytidine (CAS: 110764-78-8) should be collected in appropriate containers, labeled with the contents and hazard information. Incineration or professional waste disposal services are recommended for safe disposal. Environmental protection precautions should include minimizing spills and ensuring proper ventilation during handling.

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