Meclizine DiHCl

Basic Information

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CAS Number

1104-22-9

Molecular Formula

C25H29Cl3N2

Molecular Weight

463.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

210.0 to 214.0 deg-C

Boiling Point

495.3°Cat760mmHg

Density

1.159

Flash Point

253.3°C

Solubility

DMSO: soluble5mg/mL, clear (warmed)

SMILES

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CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl

InChI

InChI=1S/C25H27ClN2.2ClH/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;;/h2-13,18,25H,14-17,19H2,1H3;2*1H

InChIKey

VCTHNOIYJIXQLV-UHFFFAOYSA-N

LogP

6.399220000000007

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

448

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Meclizinedihydrochloride
AKOS015891690
MECLIZINE DIHYDROCHLORIDE ANHYDROUS
Q-201344
Tox21_110497
CCG-38908
NSC 28728
FT-0603544
1-[(4-Chlorophenyl)(phenyl)methyl]-4-(3-methylbenzyl)piperazine Dihydrochloride
1-p-Chlorbenzhydryl-m-methylbenzylpiperazine dihydrochloride
MECLOZINE HYDROCHLORIDE [WHO-DD]
UNII-L997QXC9J1
NSC28728
Vertizine
NCGC00094712-01
NCGC00018296-07
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine dihydrochloride
Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-, dihydrochloride
DTXCID7025348
NS00080913
L997QXC9J1
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride
DTXSID9045348
BCP0726000289
1104-22-9
Meclizine (dihydrochloride)
Taizer
MECLOZINE DIHYDROCHLORIDE [EP MONOGRAPH]
NCGC00016563-01
1104-22-9 (2HCl)
SCHEMBL2193375

MDL Number

MFCD00058199

Customs Code

2933499090

FAQ

What is Meclizine DiHCl (CAS: 1104-22-9)?

Meclizine DiHCl, also known as meclizine hydrochloride, is a chemical compound with the CAS number 1104-22-9. It is a white to off-white crystalline powder with a molecular formula of C17H18ClN2O.HCl. Meclizine DiHCl is used in pharmaceuticals as an antiemetic and antihistaminic agent, and it is often used to treat motion sickness and vertigo.

What are the main uses of Meclizine DiHCl (CAS: 1104-22-9)?

Meclizine DiHCl (CAS: 1104-22-9) is primarily used in the pharmaceutical industry as an antiemetic and antihistaminic agent. It is commonly prescribed to treat symptoms of motion sickness, vertigo, and other forms of nausea. Additionally, it may be used to alleviate the effects of inner ear disorders and other conditions causing dizziness or nausea.

Is Meclizine DiHCl (CAS: 1104-22-9) safe?

Meclizine DiHCl (CAS: 1104-22-9) is generally considered safe when used as directed. However, it may cause side effects such as drowsiness, dry mouth, and blurred vision. It is important to follow the prescribed dosage and consult a healthcare professional if any adverse effects occur. Always store the medication away from children and in a secure place to ensure safety.

How should Meclizine DiHCl (CAS: 1104-22-9) be stored?

Meclizine DiHCl (CAS: 1104-22-9) should be stored in a tightly closed container at room temperature, between 15-30°C (59-86°F), away from direct light and moisture. Avoid storing it in areas with high humidity or extreme temperatures. Keep the medication out of reach of children and pets. It is also recommended to protect the container from physical damage to maintain its integrity and efficacy.