N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine | CAS No. 109292-46-8

N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine

Basic Information

CAS Number

109292-46-8

Molecular Formula

C15H27N7O7S

Molecular Weight

449.49 g/mol

AD

Basic Physical Properties

C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CS)C(=O)O)N)CN=C(N)N

InChI

InChI=1S/C15H27N7O7S/c16-7(2-1-3-19-15(17)18)12(26)20-5-10(23)21-8(4-11(24)25)13(27)22-9(6-30)14(28)29/h7-9,30H,1-6,16H2,(H,20,26)(H,21,23)(H,22,27)(H,24,25)(H,28,29)(H4,17,18,19)/t7-,8-,9-/m0/s1

InChIKey

AEGSIYIIMVBZQU-CIUDSAMLSA-N

LogP

-3.8481299999999976

Topological Polar Surface Area

249.82000000000002 Ų

Hydrogen Bond Donor/Acceptor

11 / 14

Complexity

670

Synonyms & References

English

  • Arg-Gly-Asp-Cys
  • H-Arg-Gly-Asp-Cys-OH
  • (S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-((R)-1-carboxy-2-mercapto-ethyl)-succinamic acid
  • 109292-46-8
  • (6S,12S,15R)-1,6-diamino-12-(carboxymethyl)-1-imino-15-(mercaptomethyl)-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid
  • HY-P0314
  • BDBM50034704
  • CHEMBL290071
  • (3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-4-oxobutanoic acid
  • L-Cysteine,L-arginylglycyl-L-a-aspartyl-
  • RGDC
  • ARG-GLY-ASP-CYS
  • REF DUPL: H-Arg-Gly-Asp-Cys-OH
  • RGDC peptide

MDL Number

MFCD00076451

FAQ

What are the physical and chemical properties of N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8)?

N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8) is a cyclic dipeptide with a molecular weight of approximately 405.37 g/mol. It is slightly soluble in water and ethanol. Chemically, it is relatively stable but can react with reducing agents. It is commonly used in pharmaceutical and biochemical research.

How is N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8) typically synthesized?

N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8) is synthesized via controlled peptide coupling reactions typically using solid-phase synthesis techniques. Commonly, Boc-protected amino acids are used, and the reaction is catalyzed by carboxypeptidases or other suitable enzymes. The yield and selectivity are high, making it a reliable synthetic target for academic and industrial applications.

What industries use N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8)?

N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8) is primarily used in the pharmaceutical and biochemical industries. It serves as a key intermediate in the development of bioactive peptides and has applications in protein engineering, pharmacology, and biochemical research. Additionally, it may find use in polymer synthesis and material science due to its unique chemical structure.

What precautions should be taken when handling N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8)?

When handling N~5~-(Diaminomethylene)-L-ornithylglycyl-L-alpha-aspartyl-L-cysteine (CAS: 109292-46-8), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the substance should be disposed of according to local hazardous waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

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