Aripiprazole-d8 | CAS No. 1089115-04-7

Aripiprazole-d8

Basic Information

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CAS Number

1089115-04-7

Molecular Formula

C23H19Cl2D8N3O2

Molecular Weight

456.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

137-139°C

SMILES

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O=C1CCc2c(N1)cc(cc2)OC(C(C(C(N1CCN(CC1)c1cccc(c1Cl)Cl)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H]

InChI

InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)/i1D2,2D2,10D2,15D2

InChIKey

CEUORZQYGODEFX-BQLKVSHCSA-N

LogP

4.859300000000005

Topological Polar Surface Area

44.81 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

Aripiprazole-d8 (Butyl-d8)
7-[1,1,2,2,3,3,4,4-octadeuterio-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Aripiprazole D8
Aripiprazole-d8 solution
[2H8]-Aripiprazole
7-[4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy-d8]-3,4-dihydro-2(1H)-quinolinone
7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy-d8]-3,4-dihydro-2(1H)-quinolinone
Abilify-d8
Abilitat-d8
CTK8F7826
FT-0662279
OPC 14597-d8
OPC 31-d8
7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy-1,1,2,2,3,3,4,4-d8)-3,4-dihydroquinolin-2(1H)-one

MDL Number

MFCD08460937

FAQ

What is Aripiprazole-d8 (CAS: 1089115-04-7)?

Aripiprazole-d8 is a derivative of aripiprazole, a dopamine receptor antagonist used in the treatment of schizophrenia and bipolar disorder. It has a slightly altered chemical structure with a deuterium substitution at position 8, which is used for metabolic studies and drug development.

What are the main uses of Aripiprazole-d8 (CAS: 1089115-04-7)?

Aripiprazole-d8 (CAS: 1089115-04-7) is primarily used for pharmacokinetic and metabolic studies to better understand the behavior and fate of aripiprazole in the body. It is not used for clinical treatment but aids in the development and evaluation of new drugs.

Is Aripiprazole-d8 (CAS: 1089115-04-7) safe?

Aripiprazole-d8 is generally considered safe when handled with appropriate precautions. However, it should be used under the guidance of a trained professional due to its potential for skin and eye irritation. Proper protective measures, such as gloves and safety glasses, should be worn during handling.

How should Aripiprazole-d8 (CAS: 1089115-04-7) be stored?

Aripiprazole-d8 (CAS: 1089115-04-7) should be stored in a cool, dry place away from direct sunlight and heat sources. The container should be tightly sealed to prevent moisture and contamination. It is recommended to store at a temperature not exceeding 25°C (77°F) to ensure its stability and purity.