2-Chloropropyldimethylamine

Basic Information

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CAS Number

108-14-5

Molecular Formula

C5H12ClN

Molecular Weight

121.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Boiling Point

81.1°Cat760mmHg

Density

0.934

Flash Point

2.9°C

Refractive Index

1.432

SMILES

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CC(CN(C)C)Cl

InChI

InChI=1S/C5H12ClN/c1-5(6)4-7(2)3/h5H,4H2,1-3H3

InChIKey

GYXWNSDLDXGMGU-UHFFFAOYSA-N

LogP

1.1753

Topological Polar Surface Area

3.24 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

45.3

Synonyms & References

English

2-CHLORO-1-(DIMETHYLAMINO)PROPANE
Q27255431
(2-Chlor-propyl)-dimethylamin
Dimethylamine, N-(2-chloropropyl)-
2-Chloro-N,N-dimethyl propylamine
SCHEMBL135840
NS00023493
TL 424
AKOS009159519
UNII-2PR224F7AM
Propanamine, 2-chloro-N,N-dimethyl-
DIMETHYLAMINO ISOPROPYL CHLORIDE
1-Propanamine, 2-chloro-N,N-dimethyl-
N,N-Dimethyl-2-chloropropylamine
IP95500000
NIOSH/IP9550000
FT-0774635
EINECS 203-554-3
1-methyl-2-(N,N-dimethylamino)ethyl chloride
2PR224F7AM
N-(2-Chloropropyl)-N,N-dimethylamine #
1-dimethylamino-2-chloropropane
beta-Dimethylaminoisopropyl chloride
Propylamine, 2-chloro-N,N-dimethyl-
1-methyl-2-dimethylaminoethyl chloride
2-Chloro-1-dimethylaminopropane
N,N-Dimethyl-2-chloro propylamine
2-chloro-n,n-dimethylpropan-1-amine
2-Chloropropyldimethylamine
2-Chloro-N,N-dimethyl-1-propanamine
1-Propanamine,2-chloro-N,N-dimethyl-

MDL Number

MFCD00039345

FAQ

What are the physical and chemical properties of 2-Chloropropyldimethylamine (CAS: 108-14-5)?

2-Chloropropyldimethylamine (CAS: 108-14-5) is a colorless to slightly yellow liquid with a density of approximately 0.89 g/cm³. It has a pKa of around 10.5 and a molecular weight of 111.59 g/mol. It is slightly soluble in water but miscible with many organic solvents. The compound is moderately reactive, especially towards nucleophiles and acids.

How is 2-Chloropropyldimethylamine (CAS: 108-14-5) typically synthesized?

2-Chloropropyldimethylamine is typically synthesized by the reaction of 1-chloropropane and dimethylamine. This reaction can be carried out in the presence of a base like sodium hydride to promote the nucleophilic substitution. The process requires careful control of temperature and reagent concentration to achieve high yield and selectivity.

What industries use 2-Chloropropyldimethylamine (CAS: 108-14-5)?

2-Chloropropyldimethylamine is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for enhancing the properties of plastic materials, and as a precursor in the production of sensors and semiconductors for electronic applications.

What precautions should be taken when handling 2-Chloropropyldimethylamine (CAS: 108-14-5)?

Proper protective equipment (PPE) is essential when handling 2-Chloropropyldimethylamine (CAS: 108-14-5). Laboratory workers should wear gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.