Apabetalone | CAS No. 1044870-39-4

Apabetalone

Basic Information

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CAS Number

1044870-39-4

Molecular Formula

C20H22N2O5

Molecular Weight

370.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC1=CC(=CC(=C1OCCO)C)C2=NC3=C(C(=CC(=C3)OC)OC)C(=O)N2

InChI

InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-14(25-3)10-16(26-4)17(15)20(24)22-19/h7-10,23H,5-6H2,1-4H3,(H,21,22,24)

InChIKey

NETXMUIMUZJUTB-UHFFFAOYSA-N

LogP

2.5952400000000004

Topological Polar Surface Area

93.67000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

543

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

RVX-208
RVX 208
2-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
2-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquizolin-4(3H)-one
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-di methoxyquinazolin-4(3H)-one
2-[4-(2-Hydroxy-ethoxy)-3,5-dimethyl-phenyl]-5,7-dimethoxy-3H-quinazolin-4-one
1K0
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-3H-quinazolin-4-one
Apabetalone
CHEMBL2393130
QC-216
RVX000222
RVX-000222
SureCN145019
UNII-8R4A7GDZ1D
RVX-208(RVX 000222)
Apabetalone-RVX-208
4(3H)-Quinazolinone, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinazolinone RVX-208
2-[4-(2-Hydroxyethoxy)-3,5-Dimethylphenyl]-5,7-Dimethoxyquinazolin-4(3h)-One
RVX 000222
8R4A7GDZ1D
AK110565
Apabetalone [INN]
Apabetalone [USAN:INN]
4j3i
4mr4
4mr6
4j1p
Apabetalone (USAN/INN)
GTPL7034

MDL Number

MFCD18633270

FAQ

What is Apabetalone (CAS: 1044870-39-4)?

Apabetalone is a chemical compound with the CAS number 1044870-39-4. It is a betahydroxy-beta-methylglutaryl coenzyme A reductase (BHMG-CoA reductase) inhibitor with potential anti-inflammatory and lipid-lowering properties.

What are the main uses of Apabetalone (CAS: 1044870-39-4)?

Apabetalone is primarily used in the treatment of various cardiovascular diseases, including those associated with high cholesterol and inflammation. It is also being studied for its potential benefits in other conditions such as metabolic syndrome and type 2 diabetes.

Is Apabetalone (CAS: 1044870-39-4) safe?

Apabetalone is generally considered safe when used as directed under the supervision of a healthcare provider. However, users should be aware of potential side effects such as muscle pain, liver function abnormalities, and gastrointestinal issues. It is important to follow medical advice and report any adverse reactions promptly.

How should Apabetalone (CAS: 1044870-39-4) be stored?

Apabetalone should be stored at room temperature (15-30°C), protected from moisture and light. Keep the compound in its original container, tightly closed, and out of reach of children. Avoid exposure to extreme temperatures and ensure proper ventilation during handling.