N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (1:1) | CAS No. 103213-40-7

N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (1:1)

Basic Information

CAS Number

103213-40-7

Molecular Formula

C23H31ClN6O7

Molecular Weight

538.99 g/mol

AD

Basic Physical Properties

CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)CCCC(=O)O.Cl

InChI

InChI=1S/C23H30N6O7.ClH/c1-13-10-21(34)36-17-11-14(7-8-15(13)17)28-22(35)16(4-3-9-26-23(24)25)29-19(31)12-27-18(30)5-2-6-20(32)33;/h7-8,10-11,16H,2-6,9,12H2,1H3,(H,27,30)(H,28,35)(H,29,31)(H,32,33)(H4,24,25,26);1H/t16-;/m0./s1

InChIKey

JSJHBZGTMAWMAP-NTISSMGPSA-N

LogP

0.5808900000000017

Topological Polar Surface Area

216.70999999999995 Ų

Hydrogen Bond Donor/Acceptor

8 / 13

Complexity

899

Synonyms & References

English

  • FT-0703771
  • 103213-40-7
  • Glutaryl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride
  • N-Glutaryl-Gly-Arg-7-amido-4-methylcoumarin hydrochloride
  • Glutaryl-gly-arg-amc hcl
  • 5-[[2-[[5-(Diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid;hydrochloride
  • N-(4-Carboxybutanoyl)glycyl-N~5~-(diaminomethylidene)-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)ornithinamide--hydrogen chloride (1/1)
  • DTXSID20585162
  • L-Argininamide,N-(4-carboxy-1-oxobutyl)glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride (9CI)
  • GLUTARYLGLYCYL-L -ARGINYL-4-METHYLCOUMARYL-7-AMIDE
  • L-Argininamide,N-(4-carboxy-1-oxobutyl)glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohyd...
  • 5-[[2-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid,hydrochloride
  • GLUTARYL-GLY-ARG-AMC HCL
  • N-GLUTARYL-GLY-ARG 7-AMIDO-4-*METHYLCOUM ARIN HYDROC
  • N-Glutaryl-Gly-Arg-7-amino-4-methylcoumarin hydrobromide
  • GLUTARYL-GLYCYL-L-ARGININE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE
  • Glutaryl-Gly-Arg-AMC·HCl≥ 97% HPLC)

MDL Number

MFCD00058182

FAQ

What are the physical and chemical properties of N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (CAS: 103213-40-7)?

N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride is a crystalline compound. Its molecular weight is approximately 793.7 g/mol. It has a high solubility in water and low solubility in organic solvents. It is relatively stable under normal conditions but can react with bases to form the corresponding amide. It exhibits weak basicity due to the presence of the hydrochloride ion.

How is N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (CAS: 103213-40-7) typically synthesized?

N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride can be synthesized via the amidation of N-(4-carboxybutanoyl)glycyl-L-arginine with 7-methoxy-2-oxo-2H-chromene, followed by the addition of hydrochloric acid to form the hydrochloride salt. The reaction is catalyzed by a mild coupling reagent, and the yield is typically around 75-85%. The reaction is carried out under mild conditions to maintain the stability of the chromenone ring.

What industries use N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (CAS: 103213-40-7)?

N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride finds applications in pharmaceuticals, where it is used as a potential drug candidate for targeting specific biological pathways. It is also utilized in the preparation of advanced materials and sensors, due to its chromenone structure, which can be used in photochemical applications and sensing technologies.

What precautions should be taken when handling N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (CAS: 103213-40-7)?

When handling N-(4-Carboxybutanoyl)glycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize exposure to air and moisture. In case of a spill, it should be handled with care and cleaned up using appropriate methods, as detailed in the safety data sheet (SDS). Always follow laboratory safety guidelines and handle with caution to avoid potential health hazards.

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