1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride

Basic Information

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CAS Number

102879-34-5

Molecular Formula

C9H12ClNO

Molecular Weight

185.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

258-260 ºC

SMILES

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C1CNCC2=C1C(=CC=C2)O.Cl

InChI

InChI=1S/C9H11NO.ClH/c11-9-3-1-2-7-6-10-5-4-8(7)9;/h1-3,10-11H,4-6H2;1H

InChIKey

SKWAFWMMBSUSIB-UHFFFAOYSA-N

LogP

1.4596999999999998

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

138

Synonyms & References

English

1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride
5-HYDROXY-1, 2, 3, 4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
ACT10627
AGN-PC-00OG8E
AK101755
ANW-62704
CTK8B9555
KB-216211
SureCN1956191
1,2,3,4-TETRAHYDROISOQUINOLIN-5-OL HCL
1,2,3,4-Tetrahydro-5-isoquinolinol hydrochloride
1,2,3,4-Tetrahydroisoquinolin-5-Ol Hydrochloride(WX604738)
1,2,3,4-Tetrahydro-isoquinolin-5-ol hydrochloride
1,2,3,4-Tetrahydroisoquinolin-5-ol HCl
1,2,3,4-Tetrahydroisoquinolin-5-ol--hydrogen chloride (1/1)
CS-0035767
1,2,3,4-tetrahydroisoquinolin-5-ol,hydrochloride
SCHEMBL1956191
SY123455
EN300-7396711
DB-358996
1,2,3,4-tetrahydroisoquinolin-5-ol hydrochloric acid
DTXSID60553062
1,2,3,4-TETRAHYDROISOQUINOLIN-5-OL HYDROCHLORIDE
MFCD09880226
5-Hydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
1,2,3,4-TETRAHYDROISOQUINOLIN-5-OLHYDROCHLORIDE
1,2,3,4-tetrahydroisoquinolin-5-ol;hydrochloride
AKOS016003918
CEA87934
A26425

MDL Number

MFCD09880226

FAQ

What are the physical and chemical properties of 1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride (CAS: 102879-34-5)?

1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride is a white to off-white crystalline solid. Its molecular weight is approximately 246.69 g/mol. It is sparingly soluble in water and has good solubility in organic solvents. The compound is moderately reactive and can undergo various chemical transformations such as reduction, oxidation, and substitution reactions.

How is 1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride (CAS: 102879-34-5) typically synthesized?

1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride is commonly synthesized by the oxidation of 1,2,3,4-tetrahydroisoquinoline followed by the addition of hydrochloric acid. Commonly used catalysts include permanganate or hydrogen peroxide, and the reaction conditions are optimized for selectivity and yield.

What industries use 1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride (CAS: 102879-34-5)?

1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride is used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It is also employed in the chemical industry for the development of sensors and materials, particularly in the semiconductor industry where it can be used as a precursor for certain organic semiconductors.

What precautions should be taken when handling 1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride (CAS: 102879-34-5)?

When handling 1,2,3,4-Tetrahydroisoquinolin-5-OL hydrochloride, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be stored in a cool, dry place away from direct sunlight and moisture. In case of accidental spill, it should be cleaned up using appropriate chemicals and procedures as outlined in the safety data sheet (SDS).