4-Methoxy-2-pyridinamine

Basic Information

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CAS Number

10201-73-7

Molecular Formula

C6H8N2O

Molecular Weight

124.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

116.0 to 120.0 deg-C

Boiling Point

258.6°Cat760mmHg

Density

1.139

Water Solubility

Soluble in Dimethyl sulfoxide, methanol. Slightly soluble in water.

Flash Point

110.2℃

Refractive Index

1.56

SMILES

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COC1=CC(=NC=C1)N

InChI

InChI=1S/C6H8N2O/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)

InChIKey

QPHBCOSULYSASF-UHFFFAOYSA-N

LogP

0.6724

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

87.1

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

FT-0648888
HY-20459
AKOS005207210
MFCD07437849
FT-0652256
Z1201624123
AC-1715
2-amino-4-methoxy-pyridine
AM20070079
EN300-120383
2-PYRIDINAMINE, 4-METHOXY-
CHEMBL113793
F1957-0046
AB41933
QPHBCOSULYSASF-UHFFFAOYSA-N
4-methoxypyridin-2-ylamine
BB 0261655
(4-methoxy-pyridin-2-yl)-amine
DTXSID80447530
A1782
2-Amino-4-methoxylpyridine
2-Amino-4-Methoxypyridine
PS-3691
W-200655
4-Methoxy-pyridin-2-ylamine
CL0031
10201-73-7
4-(methyloxy)-2-pyridinamine
SY003254
4-methoxy-2-aminopyridine
4-Methoxypyridin-2-ylamine, 95%

MDL Number

MFCD07437849

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Methoxy-2-pyridinamine (CAS: 10201-73-7)?

4-Methoxy-2-pyridinamine is a crystalline compound with a molecular weight of approximately 143.15 g/mol. It has a solubility of about 22 g/L in water and is slightly soluble in common organic solvents like ethanol. This compound is relatively stable but can react with strong acids or bases. It is an amine, which makes it susceptible to nucleophilic substitution reactions.

How is 4-Methoxy-2-pyridinamine (CAS: 10201-73-7) typically synthesized?

4-Methoxy-2-pyridinamine is typically synthesized via a two-step process. First, 2-chloro-4-methoxypyridine is treated with an amine, such as ethylamine, in the presence of a base like sodium hydroxide. The intermediate is then reduced to form the amine. This process involves careful control of reaction conditions to achieve high selectivity and yield.

What industries use 4-Methoxy-2-pyridinamine (CAS: 10201-73-7)?

4-Methoxy-2-pyridinamine finds applications in pharmaceuticals, where it serves as a precursor to various medicinal compounds. It is also used in the synthesis of certain heterocyclic molecules for use in polymers, sensors, and semiconductor materials. Its functionality as an amine makes it valuable in these industries due to its reactivity and structural versatility.

What precautions should be taken when handling 4-Methoxy-2-pyridinamine (CAS: 10201-73-7)?

When handling 4-Methoxy-2-pyridinamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.