1,3-Thiazole-2-carbaldehyde

Basic Information

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CAS Number

10200-59-6

Molecular Formula

C4H3NOS

Molecular Weight

113.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

61-63 °C/15 mmHg

Refractive Index

n20/D 1.574(lit.)

SMILES

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C1=CSC(=N1)C=O

InChI

InChI=1S/C4H3NOS/c6-3-4-5-1-2-7-4/h1-3H

InChIKey

ZGTFNNUASMWGTM-UHFFFAOYSA-N

LogP

0.9555999999999998

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

76.1

Safety Information

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GHS Hazard Pictograms

H227

Hazard Statement

H227 Combustible liquid
Flammable liquids

Synonyms & References

English

AKOS005169182
BP-12619
EN300-66987
2-thiazolecarbaldehyde
TD8063
CS-W002420
Q27462131
W-200068
SCHEMBL2008395
PS-3722
Thiazole-2-carboxaldehyde
2-THIAZOLE CARBOXALDEHYDE
2-Formylthiazole
F0303
FT-0601076
MFCD00142924
Thiazolecarboxaldehyde
AM20070674
2-thiazolecaboxaldehyde
thiazole-2-carbaldehyde
2-Thiazolecarboxaldehyde, 97%
2-formyl thiazole
ZGTFNNUASMWGTM-UHFFFAOYSA-N
InChI=1/C4H3NOS/c6-3-4-5-1-2-7-4/h1-3
1,3-THIAZOLE-2-CARBOXALDEHYDE
2-Thiazolecarboxaldehyde
SCHEMBL28811
DTXSID70370565
GEO-02295
AC-33308
STR04048

MDL Number

MFCD00142924

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6)?

1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6) is a crystalline solid with a molecular weight of approximately 128.14 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards nucleophiles and reducing agents.

How is 1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6) typically synthesized?

1,3-Thiazole-2-carbaldehyde can be synthesized via the oxidation of thiazole or through the condensation of isothiocyanates with aldehydes. Common methods include using Dess-Martin periodinane or PCC for oxidation, and utilizing catalysts like tetrabutylammonium hexafluorophosphate in the condensation reaction.

What industries use 1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6)?

1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6) is used in the pharmaceutical industry for the synthesis of biologically active compounds, in the polymer industry as a precursor for polymerization, and in the sensor industry for detecting certain gases and chemicals. It also has applications in semiconductor manufacturing.

What precautions should be taken when handling 1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6)?

Proper handling of 1,3-Thiazole-2-carbaldehyde (CAS: 10200-59-6) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be done in a well-ventilated area or a fume hood due to its volatility. Spills should be handled carefully using absorbent materials, and proper disposal procedures should be followed. Always refer to the safety data sheet (SDS) for detailed instructions.