2-Bromo-5-fluoroaniline

Basic Information

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CAS Number

1003-99-2

Molecular Formula

C6H5BrFN

Molecular Weight

190.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

43.0 to 47.0 deg-C

Boiling Point

154°C/23mmHg

Density

1.6940

Refractive Index

1.456

SMILES

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C1=CC(=C(C=C1F)N)Br

InChI

InChI=1S/C6H5BrFN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2

InChIKey

FWTXFEKVHSFTDQ-UHFFFAOYSA-N

LogP

2.1704

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

99.1

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AC-3651
2-bromo-5-fluorobenzenamine
B2163
FT-0611482
5-fluoro-2-bromoaniline
CS-W001130
FWTXFEKVHSFTDQ-UHFFFAOYSA-N
2-Bromo-5-fluoroaniline, 97%
2-Bromo-5-fluoro aniline
A16198
NS00121478
CL8389
EN300-106061
Q-100018
1003-99-2
AKOS005064046
DTXSID50378367
MFCD00070750
2-bromo-5-fluoro-aniline
SCHEMBL109237
AM20060181
benzenamine, 2-bromo-5-fluoro-
PS-8400
2-Bromo-5-fluoroaniline
2-BROMO-5-FLUOROBENZENAMINE
2-Bromo-5-fluoro-phenylamine
Benzenamine, 2- bromo-5-fluoro-
2-BROMO-5-FLUORO-BENZENAMINE
2-bromo-5-fluorobenzeneamine
benzenamine,2-bromo-5-fluoro
2-Bromo-5-fluoroanil

MDL Number

MFCD00070750

Customs Code

2921420090

FAQ

What is 2-Bromo-5-fluoroaniline (CAS: 1003-99-2)?

2-Bromo-5-fluoroaniline (CAS: 1003-99-2) is a brominated and fluorinated aromatic amine with the chemical formula C6H6BrFNO. It features a benzene ring substituted with a bromo group at position 2, a fluoro group at position 5, and an amino group. This compound is known for its chemical reactivity and is commonly used as an intermediate in organic synthesis. Its physical properties include a solid appearance, moderate solubility in polar solvents, and sensitivity to light and moisture.

What are the main uses of 2-Bromo-5-fluoroaniline (CAS: 1003-99-2)?

2-Bromo-5-fluoroaniline (CAS: 1003-99-2) is primarily utilized in pharmaceutical research as a precursor for developing drugs targeting central nervous system disorders. It also serves as an intermediate in the synthesis of agrochemicals, dyes, and specialty chemicals. Additionally, its unique functional groups make it valuable in organic chemistry for creating fluorinated and brominated compounds, enhancing molecular diversity in research and industrial applications.

Is 2-Bromo-5-fluoroaniline (CAS: 1003-99-2) safe?

2-Bromo-5-fluoroaniline (CAS: 1003-99-2) requires careful handling due to its potential toxicity. It may cause skin and eye irritation, and inhalation or ingestion can lead to adverse effects. Safety standards recommend using appropriate protective equipment, such as gloves, goggles, and lab coats, and working in a well-ventilated area. Proper disposal and compliance with OSHA and REACH regulations are essential to ensure safe handling and minimize environmental impact.

How should 2-Bromo-5-fluoroaniline (CAS: 1003-99-2) be stored?

2-Bromo-5-fluoroaniline (CAS: 1003-99-2) should be stored in a sealed, cool, and dry container, away from light and moisture. It is best kept under an inert atmosphere (e.g., nitrogen) to prevent degradation. Storage conditions should maintain temperatures below 25°C and avoid exposure to humid environments. Proper labeling and adherence to chemical storage guidelines are critical to ensure stability and safety.