Compound Q&A
How is Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate (CAS: 1256824-48-2) typically synthesized?
Answer
![Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate](https://static.chemtradehub.com/structs/125/1256824-48-2-82de.webp "Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate")
Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate (CAS: 1256824-48-2) is synthesized through the condensation of ethyl isonicotinate with 1H-pyrazolo[3,4-B]pyridine using a coupling agent like 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxybenzotriazole (HOBt). This process yields a high purity product with good selectivity and a yield of approximately 85%.
About
CAS No
1256824-48-2
English Name
Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate
Molecular Formula
C9H9N3O2
Molecular Weight
191.19 g/mol
SMILES
CCOC(=O)C1=CN=C2C(=C1)C=NN2
InChIKey
DWBSMBXTDIFAGZ-UHFFFAOYSA-N
Last Updated: 2026-04-02 10:24
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