Compound Q&A

How is 1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone (CAS: 362-29-8) typically synthesized?

Answer

1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone
1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone can be synthesized through a multistep process involving the condensation of 10-(2-(dimethylamino)propyl)phenothiazine with 1-propanone. Commonly, this synthesis uses a mild base as a catalyst and is carried out in an organic solvent. The overall yield is around 70-80%, with good selectivity for the desired product.

About

CAS No 362-29-8
English Name 1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone
Molecular Formula C20H24N2OS
Molecular Weight 340.4920000000001 g/mol
SMILES CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CC(C)N(C)C
InChIKey UVOIBTBFPOZKGP-UHFFFAOYSA-N
Last Updated: 2026-04-02 05:05

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