1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone(CAS: 362-29-8)

1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone is a crystalline solid with a molecular weight of approximately 326.38 g/mol. It is slightly soluble in water but has good solubility in organic solvents like methanol and ethanol. The compound shows moderate reactivity with acidic and basic conditions. It is stable in air but should be stored in a desiccator to prevent moisture absorption.

1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone can be synthesized through a multistep process involving the condensation of 10-(2-(dimethylamino)propyl)phenothiazine with 1-propanone. Commonly, this synthesis uses a mild base as a catalyst and is carried out in an organic solvent. The overall yield is around 70-80%, with good selectivity for the desired product.

1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone is primarily used in the pharmaceutical industry for the development of certain antipsychotic drugs. It has also found applications in the semiconductor industry as a dopant material and in sensor technology for its unique electronic properties.

When handling 1-{10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}-1-propanone, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be used in a fume hood to minimize inhalation risks. Spills should be cleaned up with absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines.