Compound Q&A
How is 8-Chloro-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone (CAS: 676116-21-5) typically synthesized?
Answer
8-Chloro-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone can be synthesized via a multi-step process, starting from 4,4-dimethylquinoline. The key steps involve chlorination and dehydration reactions, often catalyzed by mercury(II) chloride or similar Lewis acids. The overall yield is around 70-80%, with excellent selectivity towards the target product. The reaction conditions require the use of anhydrous solvents and controlled temperatures to ensure product purity.
About
CAS No
676116-21-5
English Name
8-Chloro-4,4-dimethyl-3,4-dihydro-2(1H)-quinolinone
Molecular Formula
C11H12ClNO
Molecular Weight
209.67599999999996 g/mol
SMILES
O=C1Nc2c(Cl)cccc2C(C1)(C)C
InChIKey
DKDXVAZEBXCVKQ-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31
