Compound Q&A
How is Darunavir-d9 (CAS: 1133378-37-6) typically synthesized?
Answer
Darunavir-d9 (CAS: 1133378-37-6) is synthesized through multi-step reactions involving peptide coupling and ring closure. Commonly, solid-phase synthesis techniques are used, which include the use of Fmoc (fluorenylmethoxycarbonyl) protecting groups. The process involves selectivity for specific functional groups and yields around 70-80%.
About
CAS No
1133378-37-6
English Name
Darunavir-d9
Molecular Formula
C27H28D9N3O7S
Molecular Weight
556.72 g/mol
SMILES
O=C(O[C@H]1CO[C@@H]2[C@H]1CCO2)N[C@H]([C@@H](CN(C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])([2H])[2H])S(=O)(=O)c1ccc(cc1)N)O)Cc1ccccc1
InChIKey
CJBJHOAVZSMMDJ-SYUAEXFJSA-N
Last Updated: 2026-03-31 17:51
