Compound Q&A

How is Methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate (CAS: 116543-91-0) typically synthesized?

Answer

Methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate
Methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate (CAS: 116543-91-0) is typically synthesized through a condensation reaction between a fluorinated aromatic aldehyde and a chromone derivative in the presence of a catalyst such as p-toluenesulfonic acid. The process yields a high purity product with good selectivity and yield.

About

English Name Methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate
Molecular Formula C11H7FO4
Molecular Weight 222.17 g/mol
SMILES COC(=O)C1=CC(=O)C2=C(O1)C=CC(=C2)F
InChIKey IWYHARNYXQFPOB-UHFFFAOYSA-N
Last Updated: 2026-03-31 17:51

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