Compound Q&A
How is (D-Trp6,D-Leu7)-LHRH Trifluoroacetate (CAS: 321709-37-9) typically synthesized?
Answer
(D-Trp6,D-Leu7)-LHRH Trifluoroacetate is synthesized through solid-phase peptide synthesis (SPPS) followed by trifluoroacetylation of the N-terminal. Commonly, Boc-protected amino acids are used, and the synthesis involves multiple steps including coupling, deprotection, and final trifluoroacetylation. The yield is moderate to good, and the product is purified by HPLC.
About
CAS No
321709-37-9
English Name
(D-Trp6,D-Leu7)-LHRH Trifluoroacetate
Molecular Formula
C66H83F3N18O15
Molecular Weight
1425.47 g/mol
SMILES
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8.C(=O)(C(F)(F)F)O
InChIKey
KHNZXCLOURPVAS-UHFFFAOYSA-N
Last Updated: 2026-03-29 12:16
