(D-Trp6,D-Leu7)-LHRH Trifluoroacetate(CAS: 321709-37-9)

(D-Trp6,D-Leu7)-LHRH Trifluoroacetate is a crystalline compound with a molecular weight of approximately 1049.4 g/mol. It has poor aqueous solubility but good solubility in organic solvents like DMSO. This compound is known for its low reactivity under normal conditions but may react with bases. It is used in pharmaceuticals and research due to its specific biological activity.

(D-Trp6,D-Leu7)-LHRH Trifluoroacetate is synthesized through solid-phase peptide synthesis (SPPS) followed by trifluoroacetylation of the N-terminal. Commonly, Boc-protected amino acids are used, and the synthesis involves multiple steps including coupling, deprotection, and final trifluoroacetylation. The yield is moderate to good, and the product is purified by HPLC.

(D-Trp6,D-Leu7)-LHRH Trifluoroacetate is primarily used in the pharmaceutical industry for hormone research and development. It is also utilized in research laboratories for bioactivity studies and as a precursor in peptide synthesis. Some applications include diagnostic tools and potential therapeutic uses.

When handling (D-Trp6,D-Leu7)-LHRH Trifluoroacetate, wear appropriate personal protective equipment (PPE), including gloves and goggles. Work in a fume hood to minimize exposure. Store in a cool, dry place away from direct sunlight. In case of spill, neutralize with an appropriate chemical and dispose of in accordance with local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.