Compound Q&A
How is 1,3-Dichloro-5-fluoro-2-nitrobenzene (CAS: 180134-21-8) typically synthesized?
Answer
1,3-Dichloro-5-fluoro-2-nitrobenzene can be synthesized via nitration and chlorination of 5-fluoro-2-nitrobenzene. The reaction involves the gradual addition of chlorine in the presence of a Lewis acid catalyst, followed by nitration using nitric acid in the presence of sulfuric acid. Reaction conditions and catalysts can influence the yield and selectivity of the product.
About
CAS No
180134-21-8
English Name
1,3-Dichloro-5-fluoro-2-nitrobenzene
Molecular Formula
C6H2Cl2FNO2
Molecular Weight
209.99 g/mol
SMILES
C1=C(C=C(C(=C1Cl)[N+](=O)[O-])Cl)F
InChIKey
JWOMHBXKHCIYHQ-UHFFFAOYSA-N
Last Updated: 2026-03-29 08:05
