Compound Q&A
How is 8-Bromo-3-chloro-5-isopropylisoquinoline (CAS: 2660255-85-4) typically synthesized?
Answer
8-Bromo-3-chloro-5-isopropylisoquinoline is synthesized by bromination of 3-chloro-5-isopropylisoquinoline followed by bromination. The reaction is catalyzed by a Lewis acid such as aluminum bromide. The yield is typically around 70-80%, with high selectivity for the bromine substitution. The reaction is carried out under anhydrous conditions to avoid side reactions.
About
CAS No
2660255-85-4
English Name
8-Bromo-3-chloro-5-isopropylisoquinoline
Molecular Formula
C12H11BrClN
Molecular Weight
284.58 g/mol
SMILES
CC(C)c1ccc(Br)c2cnc(Cl)cc12
InChIKey
GUZXCNBBJSVUBW-UHFFFAOYSA-N
Last Updated: 2026-03-23 00:14
