Compound Q&A
How is 4-Chloro-6-(4-methylphenyl)-2-(methylsulfanyl)-5-pyrimidinecarbonitrile (CAS: 128640-74-4) typically synthesized?
Answer
4-Chloro-6-(4-methylphenyl)-2-(methylsulfanyl)-5-pyrimidinecarbonitrile is typically synthesized through a multistep reaction involving the coupling of a chlorinated pyrimidine derivative with a 4-methylphenylthioamide in the presence of an appropriate catalyst such as a Lewis acid. The reaction yields a high selectivity and a good yield, making it a reliable method for producing this compound.
About
CAS No
128640-74-4
English Name
4-Chloro-6-(4-methylphenyl)-2-(methylsulfanyl)-5-pyrimidinecarbonitrile
Molecular Formula
C13H10ClN3S
Molecular Weight
264.781 g/mol
SMILES
CC1=CC=C(C=C1)C2=C(C(=NC(=N2)SC)Cl)C#N
InChIKey
ASPBFSRVAPVCDU-UHFFFAOYSA-N
Last Updated: 2026-03-22 14:59
