Compound Q&A
How is (3beta,5beta,7beta)-3,7,14-Trihydroxybufa-20,22-dienolide (CAS: 20143-97-9) typically synthesized?
Answer
(3beta,5beta,7beta)-3,7,14-Trihydroxybufa-20,22-dienolide is typically synthesized through semi-synthetic routes from bufadienolides. Common methods include lactonization of bufadienolides followed by hydroxylation at specific positions. The synthesis usually requires the use of metal catalysts, such as palladium or platinum, and involves multi-step reactions. Yields are usually between 50-70%.
About
CAS No
20143-97-9
English Name
(3beta,5beta,7beta)-3,7,14-Trihydroxybufa-20,22-dienolide
Molecular Formula
C24H34O5
Molecular Weight
402.52 g/mol
SMILES
C[C@]12CC[C@H](O)C[C@H]1C[C@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@H](CC[C@@]21O)C1C=CC(=O)OC=1
InChIKey
IZQUQFWHNJERCJ-XKPFVIKISA-N
Last Updated: 2026-03-20 10:59
