Compound Q&A

How is 3-Amino-3-(3-hydroxyphenyl)propanoic acid (CAS: 102872-33-3) typically synthesized?

Answer

3-Amino-3-(3-hydroxyphenyl)propanoic acid
3-Amino-3-(3-hydroxyphenyl)propanoic acid is typically synthesized via the Claisen condensation between 3-hydroxybenzaldehyde and α-amino propionic acid, followed by the removal of the protecting group. Common catalysts include sodium hydroxide or potassium hydroxide, and the reaction is carried out in an aqueous medium. The overall yield is moderate to good, around 70-80%.

About

English Name 3-Amino-3-(3-hydroxyphenyl)propanoic acid
Molecular Formula C9H11NO3
Molecular Weight 181.19 g/mol
SMILES C1=CC(=CC(=C1)O)C(CC(=O)O)N
InChIKey NYHNEKBZZXSUNO-UHFFFAOYSA-N
Last Updated: 2026-03-20 02:47

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