Compound Q&A
How is (R)-2-(3,4-Difluorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS: 1049732-11-7) typically synthesized?
Answer
This compound can be synthesized via the condensation of (R)-2-(3,4-difluorobenzyl)pyrrolidine with acetic anhydride, followed by the addition of hydrochloric acid. The synthesis uses acetic anhydride as the condensing agent and hydrochloric acid for the final protonation step. The reaction yields a high purity product with high selectivity.
About
CAS No
1049732-11-7
English Name
(R)-2-(3,4-Difluorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride
Molecular Formula
C12H14ClF2NO2
Molecular Weight
277.7 g/mol
SMILES
C1CC(NC1)(CC2=CC(=C(C=C2)F)F)C(=O)O.Cl
InChIKey
YEJFDSBCFZCUFF-UTONKHPSSA-N
Last Updated: 2026-03-16 17:23
