(R)-2-(3,4-Difluorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride(CAS: 1049732-11-7)

This compound is a white crystalline solid with a molecular weight of 294.08 g/mol. It has a low solubility in water but is more soluble in organic solvents. It is moderately reactive towards bases and nucleophiles. Its melting point is around 200-210°C. The compound is chiral and exhibits good stability under normal conditions.

This compound can be synthesized via the condensation of (R)-2-(3,4-difluorobenzyl)pyrrolidine with acetic anhydride, followed by the addition of hydrochloric acid. The synthesis uses acetic anhydride as the condensing agent and hydrochloric acid for the final protonation step. The reaction yields a high purity product with high selectivity.

This compound is primarily used in the pharmaceutical industry for the development of drug candidates, particularly for central nervous system (CNS) applications. It is also used in the synthesis of certain polymers and as a precursor in sensor and semiconductor applications.

When handling this compound, safety gloves and safety goggles should be worn. Work in a well-ventilated area or fume hood to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, avoid inhaling dust and use personal protective equipment. Refer to the Material Safety Data Sheet (MSDS) for further details on handling and storage.