How is Methyl 3-(4,6-dihydroxypyrimidin-5-yl)butanoate (CAS: 1092460-40-6) typically synthesized?

Methyl 3-(4,6-dihydroxypyrimidin-5-yl)butanoate (CAS: 1092460-40-6) is typically synthesized via a multi-step process involving the condensation of 5-bromomethylpyrimidine and 3-hydroxybutanoic acid methyl ester. The reaction is catalyzed by a strong base like sodium hydride, and the product is isolated by recrystallization. The yield is moderate, around 60-70%, and the reaction is selective, giving a high yield of the desired product.