Compound Q&A

What are the physical and chemical properties of 2-Chloro-2,2-difluoroacetamide (CAS: 354-28-9)?

Answer

2-Chloro-2,2-difluoroacetamide
2-Chloro-2,2-difluoroacetamide (CAS: 354-28-9) is a colorless or white crystalline solid with a molecular weight of approximately 150.01 g/mol. It has a pKa of about 3.3. The compound is slightly soluble in water but soluble in organic solvents such as ethanol and dichloromethane. It is highly reactive, particularly towards nucleophiles and bases, and it decomposes at elevated temperatures.

About

CAS No 354-28-9
English Name 2-Chloro-2,2-difluoroacetamide
Molecular Formula C2H2ClF2NO
Molecular Weight 129.493 g/mol
SMILES C(=O)(C(F)(F)Cl)N
InChIKey PSAKKOKLSDIKEK-UHFFFAOYSA-N
Last Updated: 2026-03-10 23:59

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