Compound Q&A
How is Acetildenafil-d8 (CAS: 1189944-10-2) typically synthesized?
Answer
Acetildenafil-d8 is synthesized via a multi-step process starting from sildenafil and acetate. The reaction typically requires a strong base like sodium hydride and proceeds in an anhydrous solvent. The product is isolated by filtration and recrystallization to obtain the pure crystalline form. The yield is around 70%, and the reaction is highly selective.
About
CAS No
1189944-10-2
English Name
Acetildenafil-d8
Molecular Formula
C25H26D8N6O3
Molecular Weight
474.63 g/mol
SMILES
CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)C(=O)CN4CCN(CC4)CC)OCC)C
InChIKey
RRBRQNALHKQCAI-FUEQIQQISA-N
Last Updated: 2026-03-10 14:55
