Compound Q&A

How is (2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS: 16495-04-8) typically synthesized?

Answer

(2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate
This compound is typically synthesized through a multistep process involving the protection of a hydroxyl group, subsequent alkylation, and sulfonation. Commonly, benzyl chloride and 4-methylbenzenesulfonyl chloride are used as the starting materials. The synthesis involves reactions such as alkylation at the hydroxyl group and then sulfonation to form the final compound, with the use of catalysts and solvents to improve selectivity and yield.

About

CAS No 16495-04-8
English Name (2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate
Molecular Formula C17H20O5S
Molecular Weight 336.41 g/mol
SMILES CC1=CC=C(C=C1)S(=O)(=O)OCC(COCC2=CC=CC=C2)O
InChIKey HBMUWOSOGHUWSS-INIZCTEOSA-N
Last Updated: 2026-03-08 00:27

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