(2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate(CAS: 16495-04-8)

The compound (2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate has a crystalline form with a molecular weight of approximately 336.4 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and methanol. Chemically, it is stable under normal conditions but can react with strong acids. It is a solid at room temperature with a melting point around 140-142°C.

This compound is typically synthesized through a multistep process involving the protection of a hydroxyl group, subsequent alkylation, and sulfonation. Commonly, benzyl chloride and 4-methylbenzenesulfonyl chloride are used as the starting materials. The synthesis involves reactions such as alkylation at the hydroxyl group and then sulfonation to form the final compound, with the use of catalysts and solvents to improve selectivity and yield.

This compound is used in various industries, particularly in pharmaceuticals for drug synthesis, in polymer chemistry for the modification of polymers, and in semiconductor technology for surface treatment. It also finds applications in analytical chemistry as a reagent and in the production of sensors.

When handling (2S)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with caution and using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed information on handling and disposal.