Compound Q&A
How is 2-[(2,5-dichloropyrimidin-4-yl)amino]-N-methyl-benzamide (CAS: 761440-08-8) typically synthesized?
Answer
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2-[(2,5-Dichloropyrimidin-4-yl)amino]-N-methyl-benzamide (CAS: 761440-08-8) is typically synthesized via a multistep process involving the reaction of 2,5-dichloropyrimidine-4-amine with methylbenzoyl chloride in the presence of a suitable base such as triethylamine. The reaction yields the desired product with good selectivity and moderate to high yield, depending on the conditions.
About
CAS No
761440-08-8
English Name
2-[(2,5-dichloropyrimidin-4-yl)amino]-N-methyl-benzamide
Molecular Formula
C12H10Cl2N4O
Molecular Weight
297.145 g/mol
SMILES
CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)Cl
InChIKey
NRPNUOKRHRYIBP-UHFFFAOYSA-N
Last Updated: 2026-03-08 00:27
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