Compound Q&A
How is Biotin-PEG6-NHS ester (CAS: 2055045-04-8) typically synthesized?
Answer
Biotin-PEG6-NHS ester (CAS: 2055045-04-8) is synthesized by coupling biotin to a polyethylene glycol (PEG) chain using a NHS ester linker. The reaction involves the formation of an amide bond between the biotin amine group and the PEG-NHS ester. Commonly, this synthesis is performed in the presence of a catalytic amount of a coupling agent like DCC or EDC, with high selectivity and good yield.
About
CAS No
2055045-04-8
English Name
Biotin-PEG6-NHS ester
Molecular Formula
C29H48N4O12S
Molecular Weight
676.79 g/mol
SMILES
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O
InChIKey
QWDVPTVNWZPKBQ-LXWOLXCRSA-N
Last Updated: 2026-03-07 19:49
