Compound Q&A
How is 1-(2-Fluorobenzyl)-3-piperidinecarboxylic acid (CAS: 896046-65-4) typically synthesized?
Answer
1-(2-Fluorobenzyl)-3-piperidinecarboxylic acid is typically synthesized via the coupling of 2-fluorobenzyl chloride with 3-piperidinemethanol. The reaction is catalyzed by a suitable base like triethylamine and proceeds with good yield. The purity can be ensured by recrystallization from an appropriate solvent.
About
CAS No
896046-65-4
English Name
1-(2-Fluorobenzyl)-3-piperidinecarboxylic acid
Molecular Formula
C13H16FNO2
Molecular Weight
237.27 g/mol
SMILES
C1CC(CN(C1)CC2=CC=CC=C2F)C(=O)O
InChIKey
KOXCBDNTCRUQDS-UHFFFAOYSA-N
Last Updated: 2026-03-05 06:57
