Compound Q&A
How is (2R)-2-(4-Hydroxyphenyl)propanoic acid (CAS: 59092-88-5) typically synthesized?
Answer
(2R)-2-(4-Hydroxyphenyl)propanoic acid can be synthesized through the reduction of 2-phenylpropanoyl chloride with sodium borohydride. This method provides good yield and selectivity. Other routes include the esterification of vanillin with propionic acid, followed by acid hydrolysis to obtain the free acid form. These methods are well-documented in the literature.
About
CAS No
59092-88-5
English Name
(2R)-2-(4-Hydroxyphenyl)propanoic acid
Molecular Formula
C9H10O3
Molecular Weight
166.18 g/mol
SMILES
C[C@H](c1ccc(cc1)O)C(=O)O
InChIKey
ZHMMPVANGNPCBW-ZCFIWIBFSA-N
Last Updated: 2026-03-05 06:57
