Compound Q&A

How is 2-Carbamoyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 1213116-63-2) typically synthesized?

Answer

2-Carbamoyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine
2-Carbamoyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine is usually synthesized by the condensation of D-phenylalanine with 2-(methylthio)acetic acid followed by carbamoylation. The reaction typically proceeds under mild conditions using catalytic amounts of a suitable acid or base. The yield is around 70-80%, and the product is purified by recrystallization from an appropriate solvent.

About

English Name 2-Carbamoyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine
Molecular Formula C15H20N2O5
Molecular Weight 308.33 g/mol
SMILES O=C(OC(C)(C)C)N[C@@H](C(=O)O)Cc1ccccc1C(=O)N
InChIKey FMPVOXUPJFIODB-LLVKDONJSA-N
Last Updated: 2026-03-05 02:11

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