Compound Q&A
How is N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9) typically synthesized?
Answer
![N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide](https://static.chemtradehub.com/structs/184/1848242-58-9-ff0a.webp "N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide")
N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9) is synthesized through a multi-step process involving the condensation of 2,4-difluorobenzenesulfonamide with 5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinylamine. The synthesis typically requires the use of a base like sodium hydride and is optimized for high yield and selectivity. Proper handling of reagents and monitoring of reaction progress are crucial for successful synthesis.
About
CAS No
1848242-58-9
English Name
N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide
Molecular Formula
C20H13ClF2N4O4S
Molecular Weight
478.86 g/mol
SMILES
COc1c(cc(cn1)c2ccc3ncc(c(=O)n3c2)Cl)NS(=O)(=O)c4ccc(cc4F)F
InChIKey
LQTYGHZRBUVRMR-UHFFFAOYSA-N
Last Updated: 2026-03-04 21:35
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