N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide(CAS: 1848242-58-9)

N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9) is a crystalline compound with a molecular weight of approximately 501.26 g/mol. It is slightly soluble in water and highly soluble in organic solvents like dimethylformamide (DMF). The compound exhibits good stability under normal conditions but can be reactive towards acid and bases. It is typically used in pharmaceutical applications where its chemical properties make it suitable for specific drug formulations.

N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9) is synthesized through a multi-step process involving the condensation of 2,4-difluorobenzenesulfonamide with 5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinylamine. The synthesis typically requires the use of a base like sodium hydride and is optimized for high yield and selectivity. Proper handling of reagents and monitoring of reaction progress are crucial for successful synthesis.

N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9) is primarily used in the pharmaceutical industry. It serves as a precursor for the development of novel drugs with specific biological activities. Additionally, it may find applications in research and development for other industries such as polymers and sensors, where its unique chemical properties can be exploited.

When handling N-[5-(3-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluorobenzenesulfonamide (CAS: 1848242-58-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handling should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be promptly cleaned up using appropriate absorbents, and the area should be properly ventilated. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.