Compound Q&A
How is {2-[(4-Chlorophenyl)sulfanyl]phenyl}acetic acid (CAS: 13459-62-6) typically synthesized?
Answer
![{2-[(4-Chlorophenyl)sulfanyl]phenyl}acetic acid](https://static.chemtradehub.com/structs/134/13459-62-6-4d71.webp "{2-[(4-Chlorophenyl)sulfanyl]phenyl}acetic acid")
The synthesis of {2-[(4-Chlorophenyl)sulfanyl]phenyl}acetic acid involves the reaction of 4-chlorophenyl thiol with 2-bromoacetic acid in the presence of a base such as potassium carbonate. The reaction typically requires a solvent like dimethylformamide (DMF) and proceeds with high selectivity and good yield under basic conditions.
About
CAS No
13459-62-6
English Name
{2-[(4-Chlorophenyl)sulfanyl]phenyl}acetic acid
Molecular Formula
C14H11ClO2S
Molecular Weight
278.75 g/mol
SMILES
c1ccc(c(c1)CC(=O)O)Sc2ccc(cc2)Cl
InChIKey
WZICWIASCZNZHO-UHFFFAOYSA-N
Last Updated: 2026-01-08 21:12
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